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뇌교육 기반 명상, LDL 콜레스테롤 감소 효과 입증 (해외 학술지 게재)2019-05-31

뇌교육 기반 명상, LDL 콜레스테롤 감소 효과 입증 (해외 학술지 게재)

2019년 해외 학술지에 게재된 뇌교육 기반 명상의 효과에 관한 논문을 소개합니다.

 



'Brain education-based meditation for patients with hypertension and/or type 2 diabetes'

《Medicine》, 2019

한국뇌과학연구원-국제뇌교육종합대학원대학교-울산중구보건소

뇌교육 기반 명상의 효과를 알아보기 위해 울산중구보건소 고혈압, 당노병 환자(48명)들을 대상으로 실헙집단은 8주 간의 뇌교육 기반 명상을 비교집단은 일반적 건강 교육을 실시하였다. 본 연구의 효과성을 검증하기 위해 그룹 간 혈액에서의 LDL콜레스테롤 레벨을 측정하였고 신체적, 정신적 건강에 관한 설문지 검사를 실시하였다.

뇌교육 기반 명상의 효과를 분석한 결과 실험집단에서 혈액 내 LDL콜레스테롤 레벨이 감소하였고 염증 억제, 집중력/자신감 증가, 피로 및 화 등의 감소 효과가 있었다. 따라서 뇌교육 기반 명상이 고혈압, 당뇨병 환자의 LDL콜레스테롤 감소, 염증 억제, 긍정적 심리 상태에 효과가 있음을 알 수 있다.

[Abstract]
Background: Hypertension and type 2 diabetes are chronic diseases, which generally require lifetime care. Meditation and yoga can be complementary to pharmacological therapies according to the scientific evidences so far. Brain education-based meditation (BEM) is a technique, which has been known to change brain structure, psychology, and physiology of healthy adult participants. This randomized, nonblinded pilot trial aimed to examine whether BEM affects the conditions of patients with hypertension and/or type 2 diabetes compared with health education classes.
Methods: We randomly allocated 48 patients with hypertension and/or type 2 diabetes to BEM (n = 24) or health education (n = 24) classes in the Ulsan Junggu Public Health Center in Korea, where the classes were run during the same period and explored the impact of 8-week practice on the serum glutamic-oxaloacetic transaminase, serum glutamic pyruvic transaminase, gamma glutamyl transpeptidase, creatinine, high-density lipoprotein cholesterol, and low-density lipoprotein (LDL) cholesterol. Total RNA was extracted to examine inflammatory gene expressions from the whole blood using PAXgene blood RNA System. In addition, self-reports on mental/physical health were evaluated. The Student's t test, chi-squared test, and analysis of covariance were used for statistical analysis.
Results: The number of people who participated until the completion of the study was 14 in the control and 21 in the BEM group. After 8 weeks, LDL cholesterol level was significantly decreased in the BEM group after the intervention (13.82 mg/dL reduction, P < .05), while it was not significantly altered in the control group. The expression of inflammatory genes was significantly reduced after 8 weeks of the BEM training (0.3-, 0.5-, and 0.2-fold change for NFKB2, RELA, and IL1B, respectively, all P < .05). In the item analysis of mental/physical health self-reports, a significant improvement was confirmed as follows: increases in focus, confidence, relaxation, and happiness; decreases in fatigue, anger, and loneliness (all P < .05). There were no important adverse events or side-effects by BEM intervention.
Conclusion: Compared to health education, BEM helps lower LDL cholesterol level and the inflammatory gene expression in the patients with hypertension and/or type 2 diabetes. Moreover, BEM induces positive effects on the self-reported mental/physical states, warranting further study

[출처] ‘Brain education-based meditation for patients with hypertension and/or type 2 diabetes’, 《Medicine》, e15574, 2019
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[헤럴드경제] 한국식 명상, LDL 콜레스테롤 감소 효과 입증
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